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  2. Align Technology - Wikipedia

    en.wikipedia.org/wiki/Align_Technology

    During his treatment with a retainer intended to complete his treatment, he posited that a series of such devices could effect a large final placement in a series of small movements. He partnered with Kelsey Wirth to seek developers. [3] [4] [5] Invisalign was approved by the Food and Drug Administration in 1998, and sales began in the U.S. in ...

  3. Irvine, California - Wikipedia

    en.wikipedia.org/wiki/Irvine,_California

    Irvine (/ ˈ ɜːr v aɪ n /) is a master-planned city in central Orange County, California, United States, in the Los Angeles metropolitan area.The Irvine Company started developing the area in the 1960s and the city was formally incorporated on December 28, 1971.

  4. Beckman Laser Institute - Wikipedia

    en.wikipedia.org/wiki/Beckman_Laser_Institute

    Around 1980, Michael W. Berns, a professor of biology at the University of California, Irvine, founded an institute focusing on the then-new technology of lasers.After receiving a National Institutes of Health biotechnology grant, [3]: 328–331 he established a laboratory for laser microscopy, the Laser Microbeam Program (LAMP). [4]

  5. UC Irvine Medical Center - Wikipedia

    en.wikipedia.org/wiki/University_of_California...

    Located in the City of Orange, 13 miles from the UCI campus, UC Irvine Medical Center has 411 licensed beds and is the principal clinical facility for the teaching and research programs of the UC Irvine School of Medicine. The seven-story UC Irvine Douglas Hospital was completed in late 2011.

  6. J&J beats quarterly sales and profit estimates on cancer drug ...

    www.aol.com/news/j-j-beats-quarterly-sales...

    Quarterly sales of J&J's cancer drugs rose 19% worldwide, driven by more than $3 billion for multiple myeloma treatment Darzalex, which was up 20.9% from a year ago.

  7. Clear aligners - Wikipedia

    en.wikipedia.org/wiki/Clear_aligners

    Once the treatment period has concluded, the patient is advised to continue wearing a retainer at night for the foreseeable future. [22] When the Invisalign system was first developed, many of the aligner manufacturing processes were carried out by hand, and computer technicians had to modify each tooth in the computerized model individually. [10]

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