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Infliximab is also prescribed (out of indication) for the treatment of Behçet's disease. [35] Infliximab is the most frequently used biological agent in treating relapsing polychondritis. [36] Half of the patients saw benefit from this treatment, and a few other patients experienced infections that in some cases lead to death. [36] [37]
Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range , i.e. drugs that can easily be under- or overdosed. [ 1 ]
The incidence of developing these antibodies is highest in patients receiving intermittent therapy with infliximab, and lowest in patient receiving continuous therapy and concomitant immunosuppressive therapy. Some suggest that the presence of these antibodies causes a decrease in efficacy of infliximab and increased risk of infusion reactions.
In 2022, India Business Excellence Fund IV, a fund managed by Motilal Oswal Private Equity, invested up to ₹ 194.4 crore in Pathkind Diagnostics. The investment contributed to the company's continued development as a provider of pathology services in India. [2] In November 2021, it opened a pathology lab in Nagpur, Maharashtra. This expansion ...
It has Mutual Recognition Arrangement (MRA) with Asia Pacific Accreditation Cooperation (APAC), International Laboratory Accreditation Cooperation (ILAC). NABL is a constituent board of Quality Council of India which is an autonomous body setup under Department for Promotion of Industry and Internal Trade (DPIIT) , Ministry of Commerce and ...
In medicine and pharmacology, a trough level or trough concentration (C trough) is the concentration reached by a drug immediately before the next dose is administered, [1] [2] often used in therapeutic drug monitoring.
Thyrocare Technologies Limited is an Indian multinational chain of diagnostic and preventive care laboratories, headquartered in Navi Mumbai. [1] As of 2021, the company has a total of 1,122 outlets and collection centers across India and parts of Nepal, Bangladesh and the Middle East.
Many developed countries set up their pharmacovigilance programs following the Thalidomide scandal in the 1960s. [2] India set up its program in the 1980s. [2] This general concept of drug safety monitoring went through different forms, but the Central Drugs Standard Control Organisation established the present Pharmacovigilance Program of India in 2010. [2]