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This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets. MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (ncRNAs) that regulate gene expression by targeting messenger RNAs. [1]
StarBase; Content; Description: microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data.: Contact; Research center: Sun Yat-sen University: Laboratory: Key Laboratory of Gene Engineering of the Ministry of Education
miRBase: the microRNA database; PolymiRTS: a database of DNA variations in putative microRNA target sites; PolyQ: database of polyglutamine repeats in disease and non-disease associated proteins; Rfam: a database of RNA families; IRESbase: A comprehensive database of experimentally validated internal ribosome entry sites. [14]
miRBase grew from the microRNA registry resource set up by Sam Griffiths-Jones in 2003. [7] According to Ana Kozomara and Sam Griffiths-Jones miRBase has five aims: [1] To provide a consistent naming system for microRNAs; To provide a central place collecting all known microRNA sequences; To provide human and computer readable information for ...
Version 3.0 is an algorithm based on several parameters calculated individually for each microRNA and it combines conserved and non-conserved microRNA recognition elements into a final prediction score. human, mouse: No: Yes: webserver [129] MicroTar: An animal miRNA target prediction tool based on miRNA-target complementarity and thermodynamic ...
Cupid is a method for simultaneous prediction of miRNA-target interactions and their mediated competing endogenous RNA (ceRNA) interactions. It is an integrative approach significantly improves on miRNA-target prediction accuracy as assessed by both mRNA and protein level measurements in breast cancer cell lines.
In bioinformatics, TargetScan is a web server that predicts biological targets of microRNAs (miRNAs) by searching for the presence of sites that match the seed region of each miRNA. [1] For many species, other types of sites, known as 3'-compensatory sites [ 1 ] are also identified.
MirGeneDB is a database of manually curated microRNA genes that have been validated and annotated as initially described in Fromm et al. 2015 [1] and Fromm et al. 2020. [2] MirGeneDB 2.1 [ 3 ] includes more than 16,000 microRNA gene entries representing more than 1,500 miRNA families from 75 metazoan species and published in the 2022 NAR ...
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