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This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets. MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (ncRNAs) that regulate gene expression by targeting messenger RNAs. [1]
StarBase; Content; Description: microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data.: Contact; Research center: Sun Yat-sen University: Laboratory: Key Laboratory of Gene Engineering of the Ministry of Education
Version 3.0 is an algorithm based on several parameters calculated individually for each microRNA and it combines conserved and non-conserved microRNA recognition elements into a final prediction score. human, mouse: No: Yes: webserver [129] MicroTar: An animal miRNA target prediction tool based on miRNA-target complementarity and thermodynamic ...
miRBase grew from the microRNA registry resource set up by Sam Griffiths-Jones in 2003. [7] According to Ana Kozomara and Sam Griffiths-Jones miRBase has five aims: [1] To provide a consistent naming system for microRNAs; To provide a central place collecting all known microRNA sequences; To provide human and computer readable information for ...
It is used especially when the read length of the sequencing machine is longer than the sequenced molecule, like the microRNA case. Deconseq Detect and remove contaminations from sequence data. Erne-Filter [26] is a short string alignment package whose goal is to provide an all-inclusive set of tools to handle short (NGS-like) reads. ERNE ...
Cupid is a method for simultaneous prediction of miRNA-target interactions and their mediated competing endogenous RNA (ceRNA) interactions. It is an integrative approach significantly improves on miRNA-target prediction accuracy as assessed by both mRNA and protein level measurements in breast cancer cell lines.
In molecular biology, competing endogenous RNAs (abbreviated ceRNAs) regulate other RNA transcripts by competing for shared microRNAs (miRNAs). [1] Models for ceRNA regulation describe how changes in the expression of one or multiple miRNA targets alter the number of unbound miRNAs and lead to observable changes in miRNA activity - i.e., the abundance of other miRNA targets.
The miR-29 microRNA precursor, or pre-miRNA, is a small RNA molecule in the shape of a stem-loop or hairpin. Each arm of the hairpin can be processed into one member of a closely related family of short non-coding RNAs that are involved in regulating gene expression . [ 1 ]