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  2. Antigen-antibody interaction - Wikipedia

    en.wikipedia.org/wiki/Antigen-antibody_interaction

    Acquired immunity depends upon the interaction between antigens and a group of proteins called antibodies produced by B cells of the blood. There are many antibodies and each is specific for a particular type of antigen. Thus immune response in acquired immunity is due to the precise binding of antigens to antibody.

  3. Antibody - Wikipedia

    en.wikipedia.org/wiki/Antibody

    It is part of the B cell receptor (BCR), which allows a B cell to detect when a specific antigen is present in the body and triggers B cell activation. [42] The BCR is composed of surface-bound IgD or IgM antibodies and associated Ig-α and Ig-β heterodimers , which are capable of signal transduction . [ 43 ]

  4. Glycoprotein IIb/IIIa - Wikipedia

    en.wikipedia.org/wiki/Glycoprotein_IIb/IIIa

    In biochemistry and medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin α IIb β 3) is an integrin complex found on platelets. It is a transmembrane receptor for fibrinogen [1] and von Willebrand factor, and aids platelet activation. The complex is formed via calcium-dependent association of gpIIb and gpIIIa, a required step in ...

  5. Immunoglobulin G - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_G

    Antibodies are major components of humoral immunity. IgG is the main type of antibody found in blood and extracellular fluid, allowing it to control infection of body tissues. By binding many kinds of pathogens such as viruses, bacteria, and fungi, IgG protects the body from infection. [citation needed]

  6. Antibody-dependent cellular cytotoxicity - Wikipedia

    en.wikipedia.org/wiki/Antibody-dependent...

    Antibody-dependent cellular cytotoxicity. Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune defense whereby an effector cell of the immune system kills a target cell, whose membrane-surface antigens have been bound by specific antibodies. [1]

  7. Complement system - Wikipedia

    en.wikipedia.org/wiki/Complement_system

    Scheme of the complement system. The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. [1]

  8. Monocyte monolayer assay - Wikipedia

    en.wikipedia.org/wiki/Monocyte_monolayer_assay

    Antibodies to high prevalence red cell antigens can sometimes mask the detection of clinically significant alloantibodies because the corresponding antigen is present on most, if not all, of the screening red blood cells used to detect these antibodies possess the antigen. This is where the monocyte monolayer assay may be useful.

  9. Immune system - Wikipedia

    en.wikipedia.org/wiki/Immune_system

    Here, the immune system fails to properly distinguish between self and non-self, and attacks part of the body. Under normal circumstances, many T cells and antibodies react with "self" peptides. [119]