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Brunner syndrome is a rare genetic disorder associated with a mutation in the MAOA gene. It is characterized by lower than average IQ (typically about 85), problematic impulsive behavior (such as pyromania, hypersexuality and violence), sleep disorders and mood swings. [1] [2] It was identified in fourteen males from one family in 1993.
A dysfunctional MAOA gene has been correlated with increased aggression levels in mice, [60] [61] and has been correlated with heightened levels of aggression in humans. [62] In mice, a dysfunctional MAOA gene is created through insertional mutagenesis (called 'Tg8'). [60] Tg8 is a transgenic mouse strain that lacks functional MAO-A enzymatic ...
Dog owners are now using holistic treatments to treat their pups, holistic veterinarians and canine researchers told ABC News. Whether used as preventative care, in tandem with Western medicine or ...
Rare mutations in the gene are associated with Brunner syndrome. [medical citation needed] A study based on the Dunedin cohort concluded that maltreated children with a low-activity polymorphism in the promoter region of the MAO-A gene were more likely to develop antisocial conduct disorders than maltreated children with the high-activity ...
Forever Friends, a spin-out company from Oxford University, hopes to dramatically expand the lifespan of dogs using new gene-editing technology. This startup wants to use gene-editing to extend ...
Pat Miller wrote in Beware of the Dog: Positive Solutions for Aggressive Behavior in Dogs in 2017: "[Rage syndrome] captured the imagination of the dog world, and soon every dog with episodes of sudden, explosive aggression was tagged with the unfortunate "rage syndrome" label, especially if it was a Spaniel of any type." [16]
The FDA has approved two new treatments for sickle-cell anemia, but much remains unknown. Skip to main content. Subscriptions; Animals. Business. Fitness. Food. Games. Health. Home & Garden ...
A phylogenetic tree showing how a number of monoamine receptors are related to each other. Monoamine neurotransmitter systems occur in virtually all vertebrates, where the evolvability of these systems has served to promote the adaptability of vertebrate species to different environments.