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Keratoconus (KC) is a disorder of the eye that results in progressive thinning of the cornea. [3] The protrusion of the cornea may result in blurry vision, double vision, nearsightedness, irregular astigmatism, [4] and light sensitivity leading to poor quality-of-life. [3] [5] [6] Usually both eyes are affected. [3]
Keratoconus, a progressive, noninflammatory, bilateral, asymmetric disease, characterized by paraxial stromal thinning and weakening that leads to corneal surface distortion. [ 2 ] Keratoglobus , a rare noninflammatory corneal thinning disorder, characterised by generalised thinning and globular protrusion of the cornea.
Symptoms are not apparent until they are 1 year. Life expectancy for type A is approximately 10 to 20 years. These symptoms are seen in CS type 1 children. Cockayne syndrome type B (CSB), also known as "cerebro-oculo-facio-skeletal (COFS) syndrome" (or "Pena-Shokeir syndrome type B"), is the most severe subtype.
(H18.6) Keratoconus — degenerative disease: the cornea thins and changes shape to be more like a cone than a parabole (H19.3) Keratoconjunctivitis sicca — dry eyes (H20.0) Iritis — inflammation of the iris (H20.0, H44.1) Uveitis — inflammatory process involving the interior of the eye; Sympathetic ophthalmia is a subset.
The most common strabismus finding is large angle exotropia which can be treated by maximal bilateral eye surgery, but due to the progressive nature of the disease, strabismus may recur. [14] Those that have diplopia as a result of asymmetric ophthalmoplegia may be corrected with prisms or with surgery to create a better alignment of the eyes.
Abnormal corneal topography compromises of keratoconus, pellucid marginal degeneration, or forme fruste keratoconus with an I-S value of 1.4 or more [4] is the most significant risk factor. Low age, low residual stromal bed (RSB) thickness, low preoperative corneal thickness, and high myopia are other important risk factors.
Uveitis with poliosis of the eyelashes. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision.The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, [6] vertigo, [6] and hypoacusis), neurological (meningismus, with malaise, fever, headache, nausea, abdominal pain, stiffness of the neck and ...
Dry eye syndrome is a common eye disease. [3] It affects 5–34% of people to some degree depending on the population looked at. [5] Among older people it affects up to 70%. [10] In China it affects about 17% of people. [11] The phrase "keratoconjunctivitis sicca" means "dryness of the cornea and conjunctiva" in Latin. [12]