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Substituted and dehydro derivatives of 4-piperidinone are intermediates in alkaloid syntheses. [1] The N-protonated derivative is typically isolated as the hydrate (HO) 2 C(CH 2) 4 NH + 2. [2] It is a List I chemical in the United States as it is a precursor to fentanyl. Fentanyl synthesis using the Gupta method starting from 4-piperidone
Piperidine is an organic compound with the molecular formula (CH 2) 5 NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH 2 –) and one amine bridge (–NH–).
N-Phenethyl-4-piperidinone (NPP) is a derivative of 4-piperidinone with the molecular formula C 13 H 17 NO. It is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs such as fentanyl .
4-Pyridone exists a keto-enol tautomerism with its enol tautomer 4-hydroxypyridine. In solution, the keto tautomer is favoured, [4] and the enol tautomer only becomes important in very dilute solutions or solutions of non-polar solvents. However, the enol tautomer is dominant in the gas phase. [5]
Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione.It used to be marketed by Roche as a cough medicine available in liquid form.
4-Benzylpiperidine is a drug and research chemical used in scientific studies. It has been encountered as a designer drug. [1] Pharmacology
Piperidinones or piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko piperidone synthesis which involves combining an alkyl-1,3-acetonedicarboxylate with benzaldehyde and an amine. [1]
4-Piperidone; M. Methyprylon; P. Piperidione This page was last edited on 3 October 2022, at 12:55 (UTC). Text is available under the Creative Commons Attribution ...