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In rats, this dose was 1000 mg/kg/day, which is approximately 24 times a human dose of 200 mg twice daily based on mg/m 2 /day. In rabbits, the highest dose tested was 90 mg/kg/day, which is approximately four times a human dose of 200 mg twice daily based on mg/m 2 /day. This dose produced severe maternal toxicity and resulted in fetal ...
Cefixime, sold under the brand name Suprax among others, is an antibiotic medication used to treat a number of bacterial infections. [5] These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. [5]
Furosemide is injected either intramuscularly or intravenously, usually 0.5-1.0 mg/kg twice/day, although less before a horse is raced. As with many diuretics, it can cause dehydration and electrolyte imbalance , including loss of potassium , calcium , sodium , and magnesium .
Amisulpride is approved and used at low doses in the treatment of dysthymia and major depressive disorder. [10] [20] [11] [21] [22] [23] Whereas typical doses used in schizophrenia block postsynaptic dopamine D 2-like receptors and reduce dopaminergic neurotransmission, low doses of amisulpride preferentially block presynaptic dopamine D 2 and D 3 autoreceptors and thereby disinhibit dopamine ...
Sodium picosulfate (INN, also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is available as a generic medication .
The sodium salt faropenem sodium, available under the trade name Farom, has been marketed in Japan since 1997. ( CID 636379 from PubChem ) The prodrug form faropenem medoxomil [ 4 ] (also known as faropenem daloxate ) has been licensed from Daiichi Asubio Pharma by Replidyne , which plans to market it in conjunction with Forest Pharmaceuticals.
Saroglitazar is an insulin sensitizer.It is a first in class drug which acts as a dual PPAR agonist at the subtypes α (alpha) and γ (gamma) of the peroxisome proliferator-activated receptor (PPAR).
In at least one case, the patient had pre-existing low levels of methemoglobin reductase, [13] which likely predisposed her to the condition. It has also been reported to cause sulfhemoglobinemia. [4] [14] [15] [16] Phenazopyridine is an azo dye.