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Rasburicase, sold under the brand name Elitek in the US and Fasturtec in the EU, is a medication that helps to clear uric acid from the blood.It is a recombinant version of urate oxidase, an enzyme that metabolizes uric acid to allantoin.
Allantoin is a chemical compound with formula C 4 H 6 N 4 O 3.It is also called 5-ureidohydantoin or glyoxyldiureide. [1] [2] It is a diureide of glyoxylic acid.Allantoin is a major metabolic intermediate in most organisms including animals, plants and bacteria, though not humans.
Diazolidinyl urea is produced by the chemical reaction of allantoin and formaldehyde in the presence of sodium hydroxide solution and heat. The reaction mixture is then neutralized with hydrochloric acid and evaporated: + 4 H 2 C=O →