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Fertilization of the ovum to form a new human organism, the human zygote. (day 1 of fertilization [1]) The zygote undergoes mitotic cellular divisions, but does not increase in size. This mitosis is also known as cleavage. A hollow cavity forms marking the blastocyst stage. (day 1.5–3 of fertilization. [1])
Gestational age at birth is on average shortened by various pregnancy aspects: twin pregnancy, prelabor rupture of (fetal) membranes, pre-eclampsia, eclampsia, intrauterine growth restriction. [29] The ratio between fetal growth rate and uterine size (reflecting uterine distension) is suspected to partially determine the pregnancy length. [30]
An ultrasound showing an embryo measured to have a crown-rump length of 1.67 cm and estimated to have a gestational age of 8 weeks and 1 day. Crown-rump length (CRL) is the measurement of the length of human embryos and fetuses from the top of the head (crown) to the bottom of the buttocks (rump).
In human pregnancy, prenatal development is also called antenatal development. The development of the human embryo follows fertilization , and continues as fetal development . By the end of the tenth week of gestational age , the embryo has acquired its basic form and is referred to as a fetus .
In humans, pregnancy can be defined clinically, biochemically or biologically. Clinically, pregnancy starts from first day of the mother's last period. [4] Biochemically, pregnancy starts when a woman's human chorionic gonadotropin (hCG) levels rise above 25 mIU/mL. [5] Biologically, pregnancy starts at implantation of the fertilized egg.
Human embryology is the study of this development during the first eight weeks after fertilization. The normal period of gestation (pregnancy) is about nine months or 36 weeks. The germinal stage refers to the time from fertilization through the development of the early embryo until implantation is completed in the uterus .
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[5] [13] Pregnancy is "the presence of an implanted human embryo or fetus in the uterus"; implantation occurs on average 8–9 days after fertilization. [15] An embryo is the term for the developing offspring during the first seven weeks following implantation (i.e. ten weeks' gestational age), after which the term fetus is used until birth. [5]