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Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...
Thrombopoietin receptor agonists exhibited the greatest success so far in treating patients with refractory ITP. [37] Side effects of thrombopoietin receptor agonists include headache, joint or muscle pain, dizziness, nausea or vomiting, and an increased risk of blood clots. [31]
Fostamatinib is a drug used to treat adults with low platelet count due to chronic immune thrombocytopenia (ITP) when a prior treatment for ITP has not worked well enough. Chronic immune thrombocytopenia is an autoimmune bleeding disorder where the blood doesn't clot as it should because of a low platelet count.
Immunoglobulin therapy is the use of a mixture of antibodies (normal human immunoglobulin) to treat several health conditions. [13] [14] These conditions include primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS and measles, Guillain–Barré syndrome, and certain other infections when a ...
Rituximab can be combined with bendamustine to achieve a 71% overall and 40% complete response rate with an increased response seen with prolonged therapy (with a time to best response at a median of 30 months) due to the drugs' effect on long lived plasma cells. [4] Splenectomy is less efficacious in cold agglutinin disease. [22]
Rituximab: MabThera, Rituxan: mab: chimeric: CD20: Y [109] lymphomas, leukemias, some autoimmune disorders Rivabazumab pegol [12] mab: humanized: Pseudomonas aeruginosa type III secretion system: Robatumumab: mab: human: IGF-1 receptor (CD221) cancer Rmab: RabiShield: human: rabies virus G glycoprotein: Y: post-exposure prophylaxis of rabies ...
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