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  2. My Years of Leg Pain Turned Out to Be ALS: Why the ... - AOL

    www.aol.com/lifestyle/years-leg-pain-turned-als...

    Brooke Eby was diagnosed with ALS, or Lou Gehrig's disease, at 33 years old. It took four years for doctors to identify her condition; at the time, her primary symptom was a tightness in her calf ...

  3. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Onset of PLS usually occurs spontaneously after age 50 and progresses gradually over a number of years, or even decades. The disorder usually begins in the legs, but it may start in the tongue or the hands. Symptoms may include difficulty with balance, weakness and stiffness in the legs, and clumsiness.

  4. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    Around 50% of people with ALS die within 30 months of their symptoms beginning, about 20% live between five and ten years, [18] and about 10% survive for 10 years or longer. [19] The most common cause of death among people with ALS is respiratory failure, often accelerated by pneumonia. [18]

  5. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Symptoms of motor neuron diseases can be first seen at birth or can come on slowly later in life. Most of these diseases worsen over time; while some, such as ALS, shorten one's life expectancy, others do not. [2] Currently, there are no approved treatments for the majority of motor neuron disorders, and care is mostly symptomatic. [2]

  6. List of people with motor neuron disease - Wikipedia

    en.wikipedia.org/wiki/List_of_people_with_motor...

    Astrophysicist Stephen Hawking, whose ALS was diagnosed in 1963, had the disease for 55 years, the longest recorded time one had the disease. He died at the age of 76 in 2018. The 11th century monk Hermann of Reichenau had a lifelong disease that is considered likely to have been ALS. This would make him one of the earliest known patients of ...

  7. She Lived with These Parkinson’s Symptoms for Over a ... - AOL

    www.aol.com/lifestyle/she-lived-parkinson...

    Veronica Brown lived with chronic fatigue, depression, and anxiety for over 10 years before she learned they were early signs of Parkinson's disease. Here's how she found relief after diagnosis.

  8. 5 symptoms women over 40 should always take seriously - AOL

    www.aol.com/finance/5-symptoms-women-over-40...

    The study, which involved 106 peri- and postmenopausal women and was presented at the Endocrine Society’s annual meeting in May, indicates women should self-monitor their vasomotor symptoms and ...

  9. Amyotrophic lateral sclerosis research - Wikipedia

    en.wikipedia.org/wiki/Amyotrophic_lateral...

    Using different BAC C9orf72 transgenic mouse model, they were able to study the symptoms of ALS, such as gait abnormalities, anxiety-like behavior, reduced grip strength, and even death rates. [8] Also, the denervation of motor neurons and dysfunction of neurons can be visualized using fluorescent markers to study the neurodegenerative disorder ...