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As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. [2] As a person's condition declines, they often withdraw from family and society. [16] Gradually, bodily functions are lost, ultimately leading to death.
Late-life depression is often underdiagnosed, which is due to numerous reasons, including that depressed mood is commonly not as prominent as other somatic and psychotic symptoms such as loss of appetite, disruptions in sleep, lack of energy or anergia, fatigue, and loss of interest and enjoyment in normal life activities.
Mood swings in major depressive disorder (MDD): Various mood patterns, [69] and mood changes erratically. [37] Mood swings occur episodically and fluctuate in moderate high mood and severe low mood. [ 70 ] [ 71 ] Characterized by having high negative affect (bad mood) most of the time, particularly in melancholic subtype. [ 72 ]
Symptoms are not limited to but may include: Increased general confusion as natural light begins to fade and increased shadows appear. [4] [10] Agitation [10] and mood swings. Individuals may become fairly frustrated with their own confusion as well as aggravated by noise.
Symptoms include cognitive impairment and this usually declines further into dementia. [83] The first main symptoms of Huntington's disease often include: difficulty concentrating; memory lapses; depression - this can include low mood, lack of interest in things, or just abnormal feelings of hopelessness
Mood disorders, specifically stress-related mood disorders such as anxiety and depression, have been shown to have differing rates of diagnosis based on sex. In the United States, women are two times more likely than men to be diagnosed with a stress-related mood disorder.
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