Search results
Results From The WOW.Com Content Network
Targeted temperature management is thought to prevent brain injury by several methods, including decreasing the brain's oxygen demand, reducing the production of neurotransmitters like glutamate, as well as reducing free radicals that might damage the brain. Body temperature may be lowered by many means, including cooling blankets, cooling ...
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
The common mechanism is a free radical chain reaction, where the addition of oxygen gives rise to hydroperoxides and their associated peroxy radicals (ROO•). [5] Typically, an induction period is seen at the start where there is little activity; this is followed by a gradually accelerating take-up of oxygen, giving an autocatalytic reaction ...
“Coconut water contains antioxidants that may help neutralize harmful free radicals in the body and protect cells from oxidative stress,” explains Olszewski.
Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination). Effects of ROS on cell metabolism are well documented in a variety of species. [19] These include not only roles in apoptosis (programmed cell death) but also positive effects such as the induction of host defence [36] [37] genes ...
Simplified control circuit of human thermoregulation. [8]The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus.
The lipid hydroperoxyl radical (LOO•) can also undergo a variety of reactions to produce new radicals. [citation needed] The additional lipid radical (L•) continues the chain reaction, whilst the lipid hydroperoxide (LOOH) is the primary end product. [6] The formation of lipid radicals is sensitive to the kinetic isotope effect.
The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [1] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [2] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...