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A thrombus (pl. thrombi), colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis. There are two components to a thrombus: aggregated platelets and red blood cells that form a plug, and a mesh of cross-linked fibrin protein. The substance making up a thrombus is sometimes called cruor.
[1] [2] Typically the clot is a mural thrombus, meaning it is on the wall of the ventricle. [3] The primary risk of LVT is the occurrence of cardiac embolism , [ 1 ] [ 4 ] in which the thrombus detaches from the ventricular wall and travels through the circulation and blocks blood vessels.
Thromboembolism is a condition in which a blood clot breaks off from its original site and travels through the bloodstream (as an embolus) to obstruct a blood vessel, causing tissue ischemia and organ damage. Thromboembolism can affect both the venous and arterial systems, with different clinical manifestations and management strategies.
In terms of complications, one of the most serious occurs when the superficial blood clot is associated with a deep vein thrombosis; this can then dislodge, traveling through the heart and occluding the dense capillary network of the lungs This is a pulmonary embolism which can be life-threatening. [5]
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot.It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair.
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Typically, blood clots develop in the deep veins of the lower extremities, deep vein thrombosis (DVT) or as a blood clot in the lung, pulmonary embolism. A very small number of people who develop blood clots have a more serious and often life-threatening condition, known as thrombotic storm (TS). TS is characterized by the development of more ...
20 years ago NBC's David Bloom died after deep vein thrombosis caused a blood clot to block an artery in his lungs causing pulmonary embolism. Wife, Melanie, raises awareness.