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Anhydrous aluminium chloride is hygroscopic, having a very pronounced affinity for water. It fumes in moist air and hisses when mixed with liquid water as the Cl − ligands are displaced with H 2 O molecules to form the hexahydrate [Al(H 2 O) 6]Cl 3. The anhydrous phase cannot be regained on heating the hexahydrate.
For palmoplantar hyperhidrosis, 20% aluminum chloride hexahydrate in absolute anhydrous ethyl alcohol () is the most effective topical treatment. [4] Other topical treatments such as potassium permanganate, tannic acid (2 to 5 percent solutions), resorcinol, boric acid, formaldehyde, methenamine, and glutaraldehyde have yielded less than desirable results.
The variation most commonly used in deodorants and antiperspirants is Al 2 Cl(OH) 5 (dialuminium chloride pentahydroxide). Aluminium chlorohydrate is also used as a coagulant in water and wastewater treatment processes to remove dissolved organic matter and colloidal particles present in suspension.
Aluminum chloride hexahydrate, sold under the brand name Hydrosal Gel among others, is a first-line treatment for excessive sweating. [1] Clinical studies support the efficacy and low incidence of irritation of the 15% aluminum chloride and 2% salicylic acid gel base formula. [2] [3] [4]
Driclor is similar to other strong anti-perspirants using 20% aluminium chloride hexahydrate as the active ingredient. However, the water content and roll-on dispenser may cause skin irritancy as water / perspiration can break down the active ingredient to produce hydrochloric acid. [2] Driclor is sold only as a roll-on application bottle.
Aluminium zirconium tetrachlorohydrex gly is the INCI name for a preparation used as an antiperspirant in many deodorant products. It is selected for its ability to obstruct pores in the skin and prevent sweat from leaving the body.
Aluminium sesquichlorohydrate is an aluminium salt that is used as an antiperspirant agent, a deodorant agent, and a cosmetic astringent.Aluminium sesquichlorohydrate works by physically blocking eccrine sweat glands.
Ammonium aluminium sulfate, also known as ammonium alum or just alum (though there are many different substances also called "alum"), is a white crystalline double sulfate usually encountered as the dodecahydrate, formula (NH 4)Al(SO 4) 2 ·12H 2 O.