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Lycopenemia is a harmless skin condition caused by excessive ingestion of red foods containing lycopene, such as tomatoes, red cabbage, chili beans, and various fruits and berries, which leads to a reddish discoloration of the skin. [1]: 486
Carotenoderma is deliberately caused by beta-carotenoid treatment of certain photo-sensitive dermatitis diseases such as erythropoietic protoporphyria, where beta carotene is prescribed in quantities which discolor the skin. These high doses of beta carotene have been found to be harmless in studies, though cosmetically displeasing to some.
Lycopene may affect the immune system, the nervous system, sensitivity to sunlight, or drugs used for stomach ailments. [27] Lycopenemia is an orange discoloration of the skin that is observed with high intakes of lycopene. [15] The discoloration is expected to fade after discontinuing excessive lycopene intake. [15]
Supplementation with β-carotene did not appear to decrease the risk of cancer overall, nor specific cancers including: pancreatic, colorectal, prostate, breast, melanoma, or skin cancer generally. [107] High-dose β-carotene supplementation unexpectedly resulted in a higher incidence of lung cancer and of total mortality in people who were ...
Manhattan-based dermatologist Dr. Brendan Camp, M.D., said that toasted skin syndrome, officially known as erythema ab igne (EAI), is a "pattern of discoloration that occurs in areas of skin after ...
The free radicals are due to the action of UV light on AGE (advanced glycation end-products) as a result of the reaction of DHA with the skin, and the intermediates, such as Amadori products (a type of AGE), that lead to them. AGEs are behind the damage to the skin that occurs with high blood sugar in diabetes where similar glycation occurs. [28]