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Perlia's nucleus, also known as nucleus of Perlia and abbreviated as NP, is a spindle-shaped nucleus located in the mesencephalon, a subdivision of the Edinger-Westphal nucleus [1] [2] situated between the right and left oculomotor nuclei. It is implicated in parasympathetic oculomotor functions, possibly including input to the iris and ciliary.
The Edinger–Westphal nucleus refers to the adjacent population of non-preganglionic neurons that do not project to the ciliary ganglion, but rather project to the spinal cord, dorsal raphe nucleus, lateral septal nuclei, lateral hypothalamic area and the central nucleus of the amygdala, among other regions.
The zona incerta receives pain input through the spinothalamic tract and this has been shown to control the activity of the pain transmission pathway in the posterior thalamus. [15] Electrical or chemical stimulation of the zona incerta creates limbic-related movements, such as those associated with defense orientation and copulation. [28]
Red nucleus: This is a motor nucleus that sends a descending tract to the lower motor neurons. Substantia nigra pars compacta: This is a concentration of neurons in the ventral portion of the midbrain that uses dopamine as its neurotransmitter and is involved in both motor function and emotion. Its dysfunction is implicated in Parkinson's disease.
Hyperpathia describes the neuropathic pain which the pain threshold on one hand is elevated and the other hand is central hyperexcited whenever there is a loss of fibres. Hyperpathia is underlying the peripheral or central deafferentation when the afferent inputs are lost. [1] Hyperpathia only occurs on neuropathic pain patients with the loss ...
The ventral posterior nucleus is divided into: Ventral posterolateral nucleus, which receives sensory information from the body via the medial lemniscus, and spinothalamic tracts. Ventral posteromedial nucleus, which receives sensory information from the head and face via the trigeminal nerve.
The medial lemniscus carries axons from most of the body and terminates by synapsing with third-order neurons in the ventral posterolateral nucleus of the thalamus. [3] at the level of the mamillary bodies. Sensory axons transmitting information from the head and neck via the trigeminal nerve synapse at the ventral posteromedial nucleus of the ...
' pain receptor ') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception .