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  2. Asthma - Wikipedia

    en.wikipedia.org/wiki/Asthma

    Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.

  3. Asthma phenotyping and endotyping - Wikipedia

    en.wikipedia.org/wiki/Asthma_phenotyping_and...

    T2-low asthma is rare compared to T2-high asthma, but is often severe and refractory to inhaled corticosteroids. [1] There is a lack of targeted therapies to treat severe T2-low asthma, [ 1 ] [ 3 ] with the exception of anti-TSLP therapy, which is indicated for severe asthma regardless of etiology. [ 4 ]

  4. Asthma-COPD overlap - Wikipedia

    en.wikipedia.org/wiki/Asthma-COPD_overlap

    ACO presents with symptoms of both asthma and COPD. [1] ACO presents in adulthood, usually after the age of 40 (after there has been significant tobacco smoke or other toxic fumes exposure), with symptoms of dyspnea (shortness of breath), exercise intolerance, sputum production, cough and episodes of symptomatic worsening known as exacerbations.

  5. Pulmonary function testing - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_function_testing

    Pulmonary function testing is a safe procedure; however, there is cause for concern regarding untoward reactions and the value of the test data should be weighed against potential hazards. Some complications include dizziness, shortness of breath, coughing, pneumothorax, and inducing an asthma attack. [13] [14]

  6. Acute respiratory distress syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_respiratory_distress...

    Notably, the Berlin guidelines discourage the use of the term "acute lung injury" or ALI, as the term was commonly being misused to characterize a less severe degree of lung injury. Instead, the committee proposes a classification of ARDS severity as mild, moderate, or severe according to arterial oxygen saturation. [16]

  7. Pathophysiology of asthma - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_asthma

    The fundamental problem in asthma appears to be immunological: young children in the early stages of asthma show signs of excessive inflammation in their airways. Epidemiological findings give clues as to the pathogenesis : the incidence of asthma seems to be increasing worldwide, and asthma is now very much more common in affluent countries.

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