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With progressive liver damage; hepatocyte death and replacement of functional liver tissue with fibrosis in cirrhosis, these processes are disrupted. This leads to many of the metabolic derangements and symptoms seen in cirrhosis. [59] Cirrhosis is often preceded by hepatitis and fatty liver (steatosis), independent of the cause.
The main symptoms are usually related to the symptoms of liver cirrhosis and ascites. [4] Less often, it may be the only manifestation of chronic liver disease. The symptoms depend on many factors, such as the effusion's volume, how fast it accumulates, and the presence of cardiopulmonary disease.
Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1 ] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF ) is increasingly being recognized.
There are two main types of fatty liver disease: ... Cirrhosis. Liver cancer. High blood pressure. Type 2 diabetes. ... Symptoms of Fatty Liver Disease.
[47] [48] Alcohol-related liver disease accounts for about 4.5% of liver-related deaths globally, underscoring the substantial burden of alcohol misuse. [49] Viral hepatitis, primarily hepatitis B and hepatitis C, remains a leading cause of liver cirrhosis and liver cancer worldwide, despite advances in antiviral therapies and vaccination ...
Chronic liver disease takes several years to develop and the condition may not be recognised unless there is clinical awareness of subtle signs and investigation of abnormal liver function tests. Testing for chronic liver disease involves blood tests, imaging including ultrasound, and a biopsy of the liver. The liver biopsy is a simple ...
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