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Loratadine is also used to treat symptoms of allergies, like runny nose, congestion, and itchiness. How Claritin works. Claritin works similarly to Zyrtec, Dr. Alan says, meaning it helps block ...
[22] [27] Subsequently, other non-sedating antihistamines like loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra) were developed and introduced. [22] The introduction of the first-generation antihistamines marked the beginning of medical treatment of nasal allergies. [28]
The pharmacokinetics of cetirizine have been found to increase linearly with dose across a range of 5 to 60 mg. [3] Its C max following a single dose has been found to be 257 ng/mL for 10 mg and 580 ng/mL for 20 mg. [2] Food has no effect on the bioavailability of cetirizine but has been found to delay the T max by 1.7 hours (i.e., to ...
H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives . [ 5 ] It is also available in drug combinations such as loratadine/pseudoephedrine , in which it is combined with pseudoephedrine , a nasal decongestant . [ 5 ]
When antihistamines do work, loratadine seems to be the most effective for mild cases and doxepin most effective for more severe cases. Naltrexone, hydrocortisone, or propranolol may relieve itching for some people. [17] [7] Sertraline or other Selective serotonin reuptake inhibitors (SSRIs) is also a line of treatment. Gabapentin is very helpful.
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