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Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [8] [9] [10] For acne, it is applied to the skin as a cream, gel or ointment. [10]
Isotretinoin is the only non-psychiatric drug on the FDA's top 10 list of drugs associated with depression [57] [62] and is also within the top 10 for suicide attempts. [63] A black box warning for suicide, depression, and psychosis has been present on isotretinoin's packaging in the United States since 2005. [62]
Dr. James E. Fulton Jr., M.D., (February 25, 1940 – July 4, 2013) was an American dermatologist and medical researcher who co-invented Retin-A, a popular acne medication, in 1969. Fulton co-developed tretinoin, known by the brand name as Retin-A, with Dr. Albert Kligman.
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Acne is a skin condition characterized by clogged pores. When pores get clogged, it causes red lesions — which you know as pimples — to form on the face or other areas of the body, especially ...
Retinoic acid (simplified nomenclature for all-trans-retinoic acid) is a metabolite of vitamin A 1 (all-trans-retinol) that is required for embryonic development, male fertility, regulation of bone growth and immune function. [2]