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Interleukin 6 (IL-6) is an ... High IL-6 levels are associated with the development of encephalitis in children and immunodeficient mouse models infected with ...
Elevated interleukin-6 levels are associated with anemia, thrombocytosis, osteoporosis, and delayed growth. [ 25 ] [ 26 ] [ 27 ] Interleukin-1b also contributes significantly to disease etiology. [ 28 ]
1401 12944 Ensembl ENSG00000132693 ENSMUSG00000037942 UniProt P02741 P14847 RefSeq (mRNA) NM_000567 NM_001329057 NM_001329058 NM_001382703 NM_007768 RefSeq (protein) NP_000558 NP_001315986 NP_001315987 NP_001369632 NP_031794 Location (UCSC) Chr 1: 159.71 – 159.71 Mb Chr 1: 172.53 – 172.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse C-reactive protein (CRP) is an annular (ring ...
Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma , autoimmune diseases and prostate cancer .
Pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α also trigger pathological pain. [1] While IL-1β is released by monocytes and macrophages, it is also present in nociceptive DRG neurons. IL-6 plays a role in neuronal reaction to an injury. TNF-α is a well known proinflammatory cytokine present in neurons and the glia.
Interleukin 6 (IL6), also referred to as B-cell stimulatory factor-2 (BSF-2) and interferon beta-2, is a cytokine involved in a wide variety of biological functions. [20] It plays an essential role in the final differentiation of B cells into immunoglobulin-secreting cells, as well as inducing myeloma/plasmacytoma growth, nerve cell ...
Image source: The Motley Fool. AbbVie (NYSE: ABBV) Q4 2024 Earnings Call Jan 31, 2025, 9:00 a.m. ET. Contents: Prepared Remarks. Questions and Answers. Call ...
Castleman's disease (CD) is a rare heterogeneous lymph node disorder characterized by elevated interleukin-6 levels. Neuropathy can occur in CD patients with or without POEMS syndrome. [11] CD and POEMS tend to overlap, with roughly 15–24% of POEMS syndrome patients also having CD, with the majority having hyaline vascular type. [5]
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