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Rotigaptide is being studied for its antiarrhythmic effects, specifically for treating atrial fibrillation. [2] Atrial fibrillation is an irregular and often rapid heart rhythm. The irregular rhythm, results from abnormal electrical impulses in the heart. The irregularity can be continuous or intermittent. In atrial fibrillation, multiple ...
Atrial fibrillation is common in giant breed dogs with DCM. Doberman Pinschers more commonly have ventricular arrhythmias (e.g., premature ventricular complexes; ventricular tachycardia) that predispose them to sudden death (i.e., ventricular fibrillation). [49]
Dilated cardiomyopathy is a heritable disease in some dog breeds, including the Boxer, Dobermann, Great Dane, Irish Wolfhound, and St Bernard. [42] Treatment is based on medication, including ACE inhibitors, loop diuretics, and phosphodiesterase inhibitors. [citation needed]
Atrial fibrillation (A-fib). ... The main cause of cardiac arrest is two types of arrhythmias called ventricular fibrillation or ventricular tachycardia. ... Cardiovascular Disease Treatment.
Atrial fibrillation is associated with an increased risk of heart failure, dementia, and stroke. [3] [12] It is a type of supraventricular tachycardia. [14] Atrial fibrillation frequently results from bursts of tachycardia that originate in muscle bundles extending from the atrium to the pulmonary veins. [15]
In rabbit models, increased expression of autoantibodies has been directly correlated with induction of atrial fibrillation. [5] [6] In canine models inoculated with adrenergic autoantibodies, it has been shown that beta blockers can negate certain cardiac arrhythmias. [7]