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Mees' lines can look similar to injury to the nail, which should not be confused with true Mees' lines. [1]Mees' lines appear after an episode of poisoning with arsenic, [2] thallium or other heavy metals or selenium, [3] opioid MT-45, and can also appear if the subject is suffering from kidney failure. [4]
Leukonychia striata, transverse leukonychia, or Mees' lines are a whitening or discoloration of the nail in bands or "stria" that run parallel to the lunula (nail base). This is commonly caused by physical injury or disruption of the nail matrix.
Muehrcke's lines were described by American physician Robert C. Muehrcke (1921–2003) in 1956. In a study published in BMJ, he examined patients with known chronic hypoalbuminemia and healthy volunteers, finding that the appearance of multiple transverse white lines was a highly specific marker for low serum albumin (no subject with the sign had SA over 2.2 g/dL), was associated with severity ...
White lines across the nail (leukonychia striata, or transverse leukonychia) may be Mees' lines or Muehrcke's lines. Small white patches are known as leukonychia punctata. Dark nails are associated with B 12 deficiency. Stains of the nail plate (not the nail bed) are associated with smoking and henna use.
True leukonychia: These white spots originate from the nail matrix (where your nail grows) and appear on the nail plate, says Dr. Lal. These spots do not disappear with pressure.
It may form for different, and sometimes dangerous, reasons.
Endonyx onychomycosis is characterized by leukonychia along with a lack of onycholysis or subungual hyperkeratosis. [18] Candidal onychomycosis is Candida species invasion of the fingernails, usually occurring in persons who frequently immerse their hands in water. This normally requires the prior damage of the nail by infection or trauma.
Although less common, it is possible for fingernails to develop leukonychia striata if exposed to abnormally high lead concentrations. [52] On July 30, 2020, a report by UNICEF and Pure Earth revealed that lead poisoning is affecting children on a "massive and previously unknown scale". According to the report, one in three children, up to 800 ...