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Although diphenhydramine is widely used and generally considered to be safe for occasional usage, multiple cases of abuse and addiction have been documented. [18] Because the drug is cheap and sold over the counter in most countries, adolescents without access to more sought-after illicit drugs are particularly at risk. [99]
Buprenorphine has been shown experimentally (1982–1995) to be effective against severe, refractory depression. [3] [4] Bupropion, when sold under the brand name Wellbutrin is indicated for depression. It is also sold as a smoking cessation drug, under the name Zyban.
Desyrel – an atypical antidepressant used to treat depression and insomnia; Desoxyn (methamphetamine hydrochloride) – used to treat attention deficit hyperactivity disorder and exogenous obesity; Dexedrine (dextroamphetamine sulfate) – used to treat attention deficit hyperactivity disorder and narcolepsy
An FAA report found that between 2012 and 2016, diphenhydramine was the most common pharmaceutical known to cause impairment detected in post-mortem toxicology tests performed on someone who may have been in charge of the aircraft at the time of a fatal plane crash, specifically naming both Benadryl and Sominex.
The first-generation sedating antihistamines diphenhydramine, doxepin, doxylamine, and pyrilamine are the most widely used medications in the world for preventing and treating insomnia. [6] As of 2004, doxylamine and diphenhydramine, which are both over-the-counter medications, were the agents most commonly used to treat short-term insomnia. [11]
YES sertraline is safe and effective and typically only causes mild side effects. BUT just because most people don’t experience problems doesn’t mean you won’t have adverse reactions yourself.
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