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Vitamin D also plays a major role in calcium absorption and bone health because it helps to maintain calcium homeostasis and bone metabolism. [7] Deficiencies negatively impact parts of the teeth including the gingivae, periodontal ligaments and the alveolar bone, leading to degeneration of the teeth and jaw. [2] [9]
Bone mineral is composed mainly of calcium, which functions in skeletal mineralization during growth. [4] Puppies younger than 5 months are not able to adjust the absorption of calcium in response to intake, therefore an oversupply or undersupply can be harmful. [10] When raised on diets deficient in calcium, pathological bone fractures can ...
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[34] [35] Calcium carbonate as a calcium supplement source has several benefits compared to other forms like calcium citrate, lactate, or gluconate, because of highest content of elemental calcium by weight (40%), providing more calcium per dose compared to other forms. It is the least expensive form of calcium, making it a cost-effective ...
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It is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in the management of heart failure in dogs, most commonly caused by myxomatous mitral valve disease (also previously known as endocardiosis ), or dilated cardiomyopathy . [ 3 ]
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