Ad
related to: hippocampus and memory processing
Search results
Results From The WOW.Com Content Network
The hippocampus is located in the medial temporal lobe (subcortical), and is an infolding of the medial temporal cortex. [1] The hippocampus plays an important role in the transfer of information from short-term memory to long-term memory during encoding and retrieval stages. These stages do not need to occur successively, but are, as studies ...
The second process is systems consolidation, occurring on a much larger scale in the brain, rendering hippocampus-dependent memories independent of the hippocampus over a period of weeks to years. Recently, a third process has become the focus of research, reconsolidation , in which previously consolidated memories can be made labile again ...
The hippocampus is also involved in memory consolidation, the slow process by which memories are converted from short to long term memory. This is supported by studies in which lesions are applied to rat hippocampi at different times after learning. [2] The process of consolidation may take up to a couple years.
The dorsal CA2 and ventral CA1 subregions of the hippocampus have been implicated in social memory processing. Genetic inactivation of CA2 pyramidal neurons leads to pronounced loss of social memory, while maintaining intact sociability in mice. [ 91 ]
The hippocampus is important for explicit memory. The hippocampus is also important for memory consolidation. The hippocampus receives input from different parts of the cortex and sends its output out to different parts of the brain also. The input comes from secondary and tertiary sensory areas that have processed the information a lot already.
Studies such as these reinforce the impact that the hippocampus has on memory processing, in particular the recall function of spatial memory. Furthermore, impairment to the hippocampus can occur from prolonged exposure to stress hormones such as glucocorticoids (GCs), which target the hippocampus and cause disruption in explicit memory. [22]
The medial temporal lobe structures are critical for long-term memory, and include the hippocampal formation, perirhinal cortex, parahippocampal, and entorhinal neocortical regions. [4]: 196 [5] The hippocampus is critical for memory formation, and the surrounding medial temporal cortex is currently theorized to be critical for memory storage.
Activation in the hippocampal region associated with episodic memory encoding has been shown to occur in the rostral portion of the region whereas activation associated with episodic memory retrieval occurs in the caudal portions. [20] This is referred to as the Hippocampal memory encoding and retrieval model or HIPER model.