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A new long-acting preventive HIV drug could reach the world’s poorest countries by the end of 2025 or early 2026, a global health official told Reuters on Tuesday. The ambition is to start ...
Standard antiretroviral treatment for HIV works only on immune cells that, typical of infected cells, are actively making new viral copies. Consequently, HIV within resting cells stays under the ...
Participants included in PrEP treatment were HIV-negative. ... to look at the background incidence of HIV infection. The study found that lenacapavir injections were the most effective option for ...
Lenacapavir was approved for medical treatment in the European Union in August 2022, [10] [12] in Canada in November 2022, [5] [6] and in the United States in December 2022. [9] [11] [13] [14] It is the first of a class of drugs called capsid inhibitors to be approved by the US Food and Drug Administration (FDA) for treating HIV/AIDS. [11] [15]
It was first proposed as an HIV treatment in 2011, when in vitro tests by the Chang group provided positive results. [21] In 2014, its oral pharmokinetics in rats was elucidated. [1] A phase II study (NCT04109183) was finished in March 2019 by Genuine Biotech. In August 2020, the Chang group found that the substance inhibits vif in vitro. [22]
In November, the New England Journal of Medicine published the full results from Gilead’s Phase 3 PURPOSE 2 trial evaluating twice-yearly lenacapavir for HIV prevention. The study found that ...
Scanning electron micrograph of HIV-1, colored green, budding from a cultured lymphocyte Diagram of HIV. HIV/AIDS research includes all medical research that attempts to prevent, treat, or cure HIV/AIDS, as well as fundamental research about the nature of HIV as an infectious agent and AIDS as the disease caused by HIV.
Stopping the Virus From Replicating. Scientists first identified HIV in 1983, but the virus has been with us longer. Research suggests HIV probably infected its first human about a century ago.