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ProAir Digihaler is a breath-actuated, digital SABA inhaler with built-in flow sensors that detect, record, and store objective data. 89% (319/359) of patients met the consensus threshold of SABA ...
Knowing the indication of the drug can also help providers determine if the dose of the drug is appropriate per indication, and this can greatly improve patient safety and drug effectiveness. [ 28 ] However, there are still some challenges with incorporating the indication of use on prescription drug labels.
The ATC system also includes defined daily doses (DDDs) for many drugs. This is a measurement of drug consumption based on the usual daily dose for a given drug. According to the definition, "[t]he DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults." [15]
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The volume of distribution is 0.7-1 L/kg after a single dose, 4.7-6 L/kg after steady-state concentrations are achieved and up to 11.1 L/kg after prolonged dosing. [6] Piritramide was developed and patented in Belgium, at Janssen, in 1960. It is part of an eponymous two-member class of opioids in clinical use with the other being bezitramide ...
have a density of approximately 1.2 to 1.5 g cm −3 (approximately that of the drug to be suspended or dissolved) [16] have a vapour pressure of 40 to 80 psig [18] have no toxicity to the patient [16] [18] be non-flammable [16] [18] be able to dissolve common additives (active ingredients should be either fully soluble or fully insoluble) [16]
It often comes as a 50/50 mixture with oxygen. [1] Devices with a demand valve are available for self-administration. [5] The setup and maintenance is relatively expensive for developing countries. [6] [7] There are few side effects, other than vomiting, with short-term use. [1] [2] With long-term use anemia or numbness may occur. [2]
The drug reached phase 3 clinical trials for treatment of fatigue prior to the discontinuation of its development for this use in January 2024. [32] Aside from the preceding indications, armodafinil is currently under development for the treatment of eating disorders and, as of January 2024, is in phase 3 trials for this use.