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Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum. The word is from Ancient Greek ...
It carries with it the ductus deference, which are testicular vessels and nerves, a portion of the abdominal muscle, and lymph vessels. All of the structures remain attached to the testis and form what is known as the spermatic cord. By the time the testis is in the scrotal sac, the gubernaculum is no more than a remnant of scar like tissue. [10]
The lower part persists as the gubernaculum testis ("scrotal ligament"). This ligament secures the testis to the most inferior portion of the scrotum, tethering it in place and limiting the degree to which the testis can move within the scrotum. Cryptorchidism (undescended testes) are observed in INSL3-null male mice.
The ectopic testis can be in the perineal region, the opposite side of the scrotum, the suprapubic region, the femoral region, or the superficial inguinal pouch. [1]The ectopic testis is initially normal, but if it is ignored after childhood, it may become small and soft, with spermatogenesis arresting and interstitial cell proliferation occurring.
This is an accepted version of this page This is the latest accepted revision, reviewed on 15 February 2025. Sac of skin that protects the testicles For the obsolete dinosaur fossil name, see Megalosaurus § "Scrotum humanum". Scrotum A human's scrotum in a relaxed state (left) and a tense state (right) Details Precursor Labioscrotal swellings System Reproductive system Artery Anterior scrotal ...
The most common presentation of testicular cancer is a hard, painless lump which can be felt on one of the testis. It is either noticed by a clinician during a routine examination, or the patient themselves. [17] Risk factors for TC include: Cryptorchidism; Family history; Previous testicular cancer; The diagnosis is confirmed in different ways.
Manifestations of mixed gonadal dysgenesis are highly variable with asymmetry in gonadal development of testis and streak gonad, accounted for by the percentage of cells expressing XY genotype. [22] [23] The dysgenic testis can have an amount of functional tissue which can produce a level of testosterone, which causes masculinisation. [22] [23]
The descent of the testicles consists of the opening of a connection from the testis to its final location at the anterior abdominal wall, followed by the development of the gubernaculum, which subsequently pulls and translocates the testicle down into the developing scrotum. Ultimately, the passageway closes behind the testis.