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Evolution of a 4 mm nodular melanoma. Nodular melanoma (NM) is the most aggressive form of melanoma. [1] It tends to grow more rapidly in thickness (vertically penetrate the skin) than in diameter compared to other melanoma subtypes. [2] Instead of arising from a pre-existing mole, it may appear in a spot where a lesion did not previously exist.
The first English-language report of melanoma was presented by an English general practitioner from Stourbridge, William Norris in 1820. [165] In his later work in 1857 he remarked that there is a familial predisposition for development of melanoma (Eight Cases of Melanosis with Pathological and Therapeutical Remarks on That Disease).
Melanocytic tumors of uncertain malignant potential (MELTUMP) are melanocytic lesions in the dermis that cannot be classified by morphology as either benign naevi (moles) or malignant melanomas because the mass shows features of both.
Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).
Melanoma is a malignant proliferation of melanocytes and the most aggressive type of skin cancer. [80] [81] [82] Acral lentiginous melanoma Nodular melanoma; Amelanotic melanoma; Animal-type melanoma; Desmoplastic melanoma (neurotropic melanoma, spindled melanoma) Lentigo maligna (lentiginous melanoma on sun-damaged skin) Lentigo maligna melanoma
The diagnosis, she says, was stage 4 melanoma — but she’d never had a “dodgy mole," she shares. “It starts with a skin lesion, you look at it and ignore it, that's what I thought skin ...
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Amelanotic melanoma is a type of skin cancer in which the cells do not make any melanin. [1]: 696 [2] They can be pink, red, purple or of normal skin color, and are therefore difficult to diagnose correctly. They can occur anywhere on the body, just as a typical melanoma can.