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  2. Factor VIII - Wikipedia

    en.wikipedia.org/wiki/Factor_VIII

    Factor VIII participates in blood coagulation; it is a cofactor for factor IXa, which, in the presence of Ca 2+ and phospholipids, forms a complex that converts factor X to the activated form Xa. The factor VIII gene produces two alternatively spliced transcripts.

  3. Factor VIII (medication) - Wikipedia

    en.wikipedia.org/wiki/Factor_VIII_(medication)

    Factor VIII, an essential blood coagulation protein, [12] is used as a medication to treat and prevent bleeding in people with hemophilia A and other causes of low factor VIII. [13] [14] Certain preparations may also be used in those with von Willebrand's disease. [14] It is given by slow injection into a vein. [13]

  4. Protein C - Wikipedia

    en.wikipedia.org/wiki/Protein_C

    Factor VIII, on the other hand, is a cofactor in production of activated Factor X, which in turn converts prothrombin into thrombin. Factor VIII a augments Factor X activation by a factor of around 200,000. Because of its importance in clotting, Factor VIII is also known as anti-haemophilic factor, and deficiencies of Factor VIII cause ...

  5. Coagulation - Wikipedia

    en.wikipedia.org/wiki/Coagulation

    If a coagulation factor is part of the contact activation or tissue factor pathway, a deficiency of that factor will affect only one of the tests: Thus hemophilia A, a deficiency of factor VIII, which is part of the contact activation pathway, results in an abnormally prolonged aPTT test but a normal PT test. Deficiencies of common pathway ...

  6. Haemophilia A - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_A

    Protein structure of coagulation factor VIII, of which its deficiency is the cause of haemophilia A. Specialty: Haematology: Symptoms: Prolonged bleeding from common injuries [1] Causes: Factor VIII deficiency [2] Diagnostic method: Bleeding time, [2] coagulation screen, genetic testing: Prevention: Hepatitis B vaccine should be considered [2 ...

  7. ATC code B02 - Wikipedia

    en.wikipedia.org/wiki/ATC_code_B02

    B02BD01 Coagulation factor IX, II, VII and X in combination (Prothrombin complex concentrate) B02BD02 Coagulation factor VIII B02BD03 Factor VIII inhibitor bypassing activity B02BD04 Coagulation factor IX B02BD05 Coagulation factor VII B02BD06 von Willebrand factor and coagulation factor VIII in combination B02BD07 Coagulation factor XIII

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