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Included in MAPS' research efforts are MDMA (methylenedioxymethamphetamine) for the treatment of posttraumatic stress disorder (PTSD); LSD and psilocybin for the treatment of anxiety, cluster headaches, and depression associated with end-of-life issues; ibogaine for the treatment of opiate addiction, ayahuasca for the treatment of drug ...
Alcohol use disorder (AUD) is the leading cause of SUD amongst veterans who have experienced trauma. [7] While research indicates that alcohol is the most abused substance by those diagnosed with PTSD, additional substances with high abuse rates include other depressants such as cannabis and opiates, as well as the stimulant cocaine." [8]
[14] [17] The United States Food and Drug Administration has granted "breakthrough therapy" status, which expedites the potential approval of promising drug therapies, [note 2] to psychedelic therapies using psilocybin (for treatment-resistant depression and major depressive disorder) [8] and MDMA (for post-traumatic stress disorder).
More than 50% of those with PTSD have co-morbid anxiety, mood, or substance use disorders. [37] Substance use disorder, such as alcohol use disorder, commonly co-occur with PTSD. [38] Recovery from post-traumatic stress disorder or other anxiety disorders may be hindered, or the condition worsened, when substance use disorders are comorbid with ...
A phase III study indicated that MDMA-assisted therapy represents a potential breakthrough treatment for severe PTSD that merits expedited clinical evaluation. [17] Based on this study, MDMA-assisted psychotherapy was granted breakthrough therapy designation by the FDA, a designation that indicates that there is preliminary evidence that an intervention might offer a substantial improvement ...
Complex post-traumatic stress disorder (CPTSD, cPTSD, or hyphenated C-PTSD) is a stress-related mental and behavioral disorder generally occurring in response to complex traumas [1] (i.e., commonly prolonged or repetitive exposures to a series of traumatic events, from which one sees little or no chance to escape).