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Post-cardiac arrest syndrome (PCAS) is an inflammatory state of pathophysiology that can occur after a patient is resuscitated from a cardiac arrest. [1] While in a state of cardiac arrest, the body experiences a unique state of global ischemia .
Targeted temperature management (TTM), previously known as therapeutic hypothermia or protective hypothermia, is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. [1]
For management of pediatric cardiac arrest, CPR should be initiated if suspected. Guidelines provide algorithms for pediatric cardiac arrest management. Recommended medications during pediatric resuscitation include epinephrine, lidocaine, and amiodarone. [162] [81] [82] However, the use of sodium bicarbonate or calcium is not recommended.
In the 1980s, the use of hypothermia on dogs after cardiac arrest demonstrated positive outcomes, including neurological status and survival. In 2005, the American Heart Association implemented recommendations and guidelines for mild hypothermia in post-resuscitation support after cardiac arrest with return of spontaneous circulation. [2]
In cardiac arrest, the heart quivers with uncoordinated contractions, and the blood flow to every part of the body — including the brain — ceases. Unlike a heart attack, in which the heart ...
Patients with sustained ROSC generally present with post-cardiac arrest syndrome (PCAS). Longer time-to-ROSC is associated with a worse presentation of PCAS. [9] Lazarus phenomenon is the rare spontaneous return of circulation after cardiopulmonary resuscitation attempts have stopped in someone with cardiac arrest. This phenomenon most ...
Abella has conducted research on sudden cardiac arrest, myocardial perfusion and targeted temperature management. He has also worked on evaluation of CPR and resuscitation performance, testing of new teaching methods of CPR, assessment of neurologic outcomes after cardiac arrest and methods to improve the application of therapeutic hypothermia.
The ELSO registry has been instrumental in improving ECMO care, post-cardiac arrest management, pediatric ventricular assist devices, and organ transplantation. [9] The last formally published ELSO Registry report was in 2017, and contained clinical characteristics, complications, and outcomes of 78,397 patients supported with ECMO. [10]