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Fluconazole is contraindicated in patients who: [14] Drink alcohol; have known hypersensitivity to other azole medicines such as ketoconazole; [2] are taking terfenadine, if 400 mg per day multidose of fluconazole is administered; [2] concomitant administration of fluconazole and quinidine, especially when fluconazole is administered in high ...
In most cases, the diagnosis is established based on response to therapy. Patients in whom esophageal candidiasis is suspected should receive a brief course of antifungal therapy with fluconazole. If the infection resolves after treatment with fluconazole, then the diagnosis of esophageal candidiasis is made and no further investigation is needed.
The most I have seen recommended for Vulvovaginal Candidiasis or Candidal Balanitis is one single dosage of Fluconazole (150mg), then a possible 2nd and 3rd dosage 3 and 6 days later respectively for severe or recurring infections (a medical provider and friend has suggested a dosage of one 150mg tablet followed by a 2nd and final dose 48 hours ...
Ibrexafungerp is indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). [1] [4]Ibrexafungerp is currently undergoing late-stage clinical trials for an intravenous formulation for the treatment of various fungal diseases, including life-threatening fungal infections caused primarily by Candida (including C. auris) and Aspergillus species.
However, ketoconazole has largely been replaced as a first-line systemic antifungal medication by other azole antifungal agents, such as fluconazole and/or itraconazole, because of ketoconazole's greater toxicity, poorer absorption, and more limited spectrum of activity.
Flucytosine must not be used as a sole agent in life-threatening fungal infections due to relatively weak antifungal effects and fast development of resistance, but rather in combination with amphotericin B and/or azole antifungals such as fluconazole or itraconazole. Minor infections such as candidal cystitis may be treated with flucytosine alone.