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  2. Anti-asthmatic agent - Wikipedia

    en.wikipedia.org/wiki/Anti-asthmatic_agent

    The goal of asthmatic agents is to reduce asthma exacerbation frequencies and related hospital visits. Anti-asthmatic agents as rescue medications for acute asthma attacks include short-acting β 2-adrenergic receptor agonists (SABA), short-acting muscarinic antagonists (SAMA), systemic glucocorticoids, and magnesium sulfate.

  3. Arachidonate 5-lipoxygenase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Arachidonate_5-lipoxygen...

    The overproduction of leukotrienes is a major cause of inflammation in asthma, ... Examples of 5-LOX inhibitors include the pharmaceutical drugs meclofenamate ...

  4. Asthma - Wikipedia

    en.wikipedia.org/wiki/Asthma

    Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.

  5. Formoterol - Wikipedia

    en.wikipedia.org/wiki/Formoterol

    Formoterol, also known as eformoterol, is a long-acting β 2 agonist (LABA) used as a bronchodilator in the management of asthma and chronic obstructive pulmonary disease (COPD). Formoterol has an extended duration of action (up to 12 h) compared to short-acting β 2 agonists such as salbutamol (albuterol), which are effective for 4 h to 6 h.

  6. Mast cell stabilizer - Wikipedia

    en.wikipedia.org/wiki/Mast_cell_stabilizer

    Mast cell stabilizers are medications used to prevent or treat certain allergic disorders. They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected pharmacodynamic mechanism is the blocking of IgE-regulated calcium channels. Without intracellular calcium, the ...

  7. Long-acting beta-adrenoceptor agonist - Wikipedia

    en.wikipedia.org/wiki/Long-acting_beta...

    With the exception of formoterol, LABAs are not recommended for the treatment of acute asthma exacerbations because of their slower onset of action compared to salbutamol. Their long duration of action is due to the addition of a long lipophilic side-chain that binds to an exosite on adrenergic receptors.

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