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  2. Phenylpropanolamine - Wikipedia

    en.wikipedia.org/wiki/Phenylpropanolamine

    Phenylpropanolamine was first synthesized in the early 20th century, in or around 1910. [21] [11] It was patented as a mydriatic in 1913. [21] The pressor effects of phenylpropanolamine were characterized in the late 1920s and the 1930s. [21] Phenylpropanolamine was first introduced for medical use by the 1930s. [23] [11]

  3. Penicillin-binding proteins - Wikipedia

    en.wikipedia.org/wiki/Penicillin-binding_proteins

    Resistance to antibiotics has come about through overproduction of PBPs and formation of PBPs that have low affinity for penicillins (among other mechanisms such as lactamase production). These experiments change the structure of PBP by adding different amino acids into the protein, allowing for new discovery of how the drug interacts with the ...

  4. Substituted β-hydroxyamphetamine - Wikipedia

    en.wikipedia.org/wiki/Substituted_β...

    Some β-hydroxyamphetamines have had their side chain extended and cyclized.Examples include certain substituted phenylmorpholines like phenmetrazine and phendimetrazine and their analogues; substituted phenylmorpholines related to bupropion like radafaxine (cyclized (2S,3S)-hydroxybupropion) and manifaxine; certain substituted aminorexes like 4-methylaminorex and 4,4'-dimethylaminorex; and ...

  5. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    The following is a list of antibiotics. ... Interact with the Gram-negative bacterial outer membrane and cytoplasmic membrane, displacing bacterial counterions, which ...

  6. Propanolamines - Wikipedia

    en.wikipedia.org/wiki/Propanolamines

    Propanolamines are a class of chemical compounds, many of which are pharmaceutical drugs. They are amino alcohols that are derivatives of 1-amino-2-propanol. [1] Propanolamines include: Acebutolol; Atenolol; Betaxolol; Bisoprolol; Metoprolol; Nadolol; Penbutolol; Phenylpropanolamine; Pindolol; Practolol; Propranolol; Ritodrine; Timolol

  7. Sympathomimetic drug - Wikipedia

    en.wikipedia.org/wiki/Sympathomimetic_drug

    The mechanisms of sympathomimetic drugs can be direct-acting (direct interaction between drug and receptor), such as α-adrenergic agonists, β-adrenergic agonists, and dopaminergic agonists; or indirect-acting (interaction not between drug and receptor), such as MAOIs, COMT inhibitors, release stimulants, and reuptake inhibitors that increase the levels of endogenous catecholamines.

  8. Antibiotic synergy - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_synergy

    Some research is devoted to finding combinations of extant antibiotics which when combined exhibit synergy. A classic example of this effect is the interaction between β-lactams, which damage the bacteria cell membrane, and aminoglycosides, which inhibit protein synthesis. [1]

  9. Chlorphenamine - Wikipedia

    en.wikipedia.org/wiki/Chlorphenamine

    Chlorphenamine is often combined with phenylpropanolamine to form an allergy medication with both antihistamine and decongestant properties, though phenylpropanolamine is no longer available in the US after studies showed it increased the risk of stroke in young women. [7] Chlorphenamine remains available with no such risk.