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Phenylpropanolamine was first synthesized in the early 20th century, in or around 1910. [21] [11] It was patented as a mydriatic in 1913. [21] The pressor effects of phenylpropanolamine were characterized in the late 1920s and the 1930s. [21] Phenylpropanolamine was first introduced for medical use by the 1930s. [23] [11]
The original packaging used the phrase "Ayds Reducing Plan vitamin and mineral Candy"; a later version used the phrase "appetite suppressant candy". The active ingredient was originally benzocaine, [1] presumably to reduce the sense of taste to reduce eating, later changed in the candy (as reported by The New York Times) to phenylpropanolamine. [2]
Phenylpropanolamine pIA Prenylamine Propylamphetamine Pseudoephedrine Selegiline (L-deprenyl) Tiflorex Tyramine Xylopropamine Zylofuramine Piperazines Benzylpiperazine (BZP) 2,5-Dimethoxy-4-bromobenzylpiperazine (2C-B-BZP) Methylbenzylpiperazine (MBZP) Metachlorophenylpiperazine (mCPP) Methylenedioxybenzylpiperazine (MDBZP ...
Plant extract sold as a dietary supplement: Contains ephedrine, an adrenergic agonist: Banned in 2004 for safety reasons 0.9 kilograms (2.0 lb) per month more than placebo [75] Amphetamine salts: Obetrol: Approved 1960, withdrawn 1973; Adderall was later approved for ADHD and narcolepsy and is still used for those purposes Phenylpropanolamine
Some β-hydroxyamphetamines have had their side chain extended and cyclized.Examples include certain substituted phenylmorpholines like phenmetrazine and phendimetrazine and their analogues; substituted phenylmorpholines related to bupropion like radafaxine (cyclized (2S,3S)-hydroxybupropion) and manifaxine; certain substituted aminorexes like 4-methylaminorex and 4,4'-dimethylaminorex; and ...
Dexatrim is an over-the-counter (OTC) dietary supplement meant to assist with weight loss. Dexatrim claims it "gives you the power to lose weight, curb binges, and keep you in control of your diet." Dexatrim claims it "gives you the power to lose weight, curb binges, and keep you in control of your diet."
Oxilofrine, sold under the brand names Carnigen and Suprifen among others, is a sympathomimetic medication which has been used as an antihypotensive agent and cough suppressant.
Phenylpropanolamine (PPA; Accutrim; β-hydroxyamphetamine), also known as the stereoisomers norephedrine and norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes that is used as a stimulant, decongestant, and anorectic agent. [156]