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The Common Terminology Criteria for Adverse Events (CTCAE), [1] formerly called the Common Toxicity Criteria (CTC or NCI-CTC), are a set of criteria for the standardized classification of adverse events of drugs and treatment used in cancer therapy. The CTCAE system is a product of the US National Cancer Institute (NCI).
During anaesthesia, carbon tetrachloride has caused such violent muscular contractions and negative effects on the heart in some patients that it had to be replaced with chloroform or ether. [55] [59] Such use was experimental and the anaesthetic use of carbon tetrachloride never gained popularity due to its potential toxicity.
Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. [1] The normal serum range for chloride is 96 to 106 mEq/L, [2] therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. [3]
Negative values of the decimal logarithm of the median lethal dose LD 50 (−log 10 (LD 50)) on a linearized toxicity scale encompassing 11 orders of magnitude. Water occupies the lowest toxicity position (1) while the toxicity scale is dominated by the botulinum toxin (12). [107] The LD 50 values have a very wide range.
Salt poisoning is an intoxication resulting from the excessive intake of sodium (usually as sodium chloride) either in solid form or in solution (saline water, including brine, brackish water, or seawater). Salt poisoning sufficient to produce severe symptoms is rare, and lethal salt poisoning is possible but even rarer.
Mercury(II) chloride (or mercury bichloride [citation needed], mercury dichloride), historically also known as sulema or corrosive sublimate, [2] is the inorganic chemical compound of mercury and chlorine with the formula HgCl 2, used as a laboratory reagent.
Chlorine gas poisoning is an illness resulting from the effects of exposure to chlorine beyond the threshold limit value.Acute chlorine gas poisoning primarily affects the respiratory system, causing difficulty breathing, cough, irritation of the eyes, nose, and throat, and sometimes skin irritation.
Tubocurarine (also known as d-tubocurarine or DTC) is a toxic benzylisoquinoline alkaloid historically known for its use as an arrow poison.In the mid-1900s, it was used in conjunction with an anesthetic to provide skeletal muscle relaxation during surgery or mechanical ventilation.