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  2. Vagusstoff - Wikipedia

    en.wikipedia.org/wiki/Vagusstoff

    Vagusstoff (literally translated from German as "Vagus Substance") refers to the substance released by stimulation of the vagus nerve which causes a reduction in the heart rate. Discovered in 1921 by physiologist Otto Loewi , vagusstoff was the first confirmation of chemical synaptic transmission and the first neurotransmitter ever discovered.

  3. Otto Loewi - Wikipedia

    en.wikipedia.org/wiki/Otto_Loewi

    His experiment was iconic because it was the first to demonstrate the endogenous release of a chemical substance that could cause a response in the absence of electrical stimulation. It paved the way for the understanding that the electrical signaling event (action potential) causes a chemical event (release of neurotransmitter from synapses ...

  4. History of catecholamine research - Wikipedia

    en.wikipedia.org/wiki/History_of_catecholamine...

    Vagusstoff transmitted inhibition from the vagus nerves, and Acceleransstoff transmitted stimulation from the sympathetic nerves to the heart. [31] Loewi took some years to commit himself with respect to the nature of the Stoffe , but in 1926 he was sure that Vagusstoff was acetylcholine, writing in 1936 [ 32 ] "I no longer hesitate to identify ...

  5. Organ bath - Wikipedia

    en.wikipedia.org/wiki/Organ_bath

    The 1921 discovery by Otto Loewi of Vagusstoff using frog hearts resulted in the identification of acetylcholine as the first neurotransmitter. [10] Enkephalin using bioassays such as the mouse vas deferens as a bioassay. [11] Nitric oxide using both assays of bull retractor penis and aortic ring. [12]

  6. File:Experiments.pdf - Wikipedia

    en.wikipedia.org/wiki/File:Experiments.pdf

    Page:Experiments.pdf/26; Metadata. This file contains additional information, probably added from the digital camera or scanner used to create or digitize it.

  7. Behavioral sink - Wikipedia

    en.wikipedia.org/wiki/Behavioral_sink

    "Behavioral sink" is a term invented by ethologist John B. Calhoun to describe a collapse in behavior that can result from overpopulation.The term and concept derive from a series of over-population experiments Calhoun conducted on Norway rats between 1958 and 1962. [1]

  8. Edgewood Arsenal human experiments - Wikipedia

    en.wikipedia.org/wiki/Edgewood_Arsenal_human...

    The LSD experiments are perhaps the best documented of the psychochemical experiments of the time, garnering at least two significant independent reports. [ 4 ] [ 33 ] [ 34 ] LSD is a Psychedelic drug that acts as a dopamine and serotonin agonist [ 35 ] [ 36 ] precipitating a hallucinogenic effect, leading to hallucinations , euphoria , and a ...

  9. Talk:Vagusstoff - Wikipedia

    en.wikipedia.org/wiki/Talk:Vagusstoff

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