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Adrenal fatigue or hypoadrenia is a pseudo-scientific term used by alternative medicine providers to suggest that the adrenal glands are exhausted and unable to produce adequate quantities of hormones, primarily cortisol, due to chronic stress or infections. [1]
Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones. The adrenal glands—also referred to as the adrenal cortex—normally secrete glucocorticoids (primarily cortisol), mineralocorticoids (primarily aldosterone), and androgens.
Hypoaldosteronism causes low sodium (hyponatremia), high potassium (hyperkalemia), and metabolic acidosis, a condition in which the body produces excess acid.These conditions are responsible for the symptoms of hypoaldosteronism, which include muscle weakness, nausea, palpitations, irregular heartbeat, and abnormal blood pressure.
There is some evidence of the existence of a so-called "adrenergic postprandial syndrome": the blood glucose level is normal, and the symptoms are caused through autonomic adrenergic response. [6] Often, this syndrome is associated with emotional distress and anxious behaviour of the patient. [7] [8]
The most disseminated version of burnout was developed by Christina Maslach, and is defined by the triad of emotional exhaustion, cynicism and an experience of reduced professional capacity. [ 90 ] [ 88 ] The syndrome of burnout was initially exclusively focused on occupation related stress-inducers, but was later expanded to include other ...
Rapid onset of symptoms indicates acute adrenal failure, which is a clinical emergency. [5] An adrenal crisis can be triggered by stress, such as from an injury, surgery, or infection. [1] Addison's disease arises when the adrenal gland does not produce sufficient amounts of the steroid hormones cortisol and (sometimes) aldosterone. [1]