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  2. John Crowley (businessman) - Wikipedia

    en.wikipedia.org/wiki/John_Crowley_(businessman)

    In 1998, two of Crowley's children, Megan and Patrick, were diagnosed with a severe neuromuscular disorder glycogen storage disease type II, also called Pompe disease. In the face of the children's deteriorating health, the family moved to Princeton, New Jersey to be close to doctors specializing in the disease.

  3. Extraordinary Measures (film) - Wikipedia

    en.wikipedia.org/wiki/Extraordinary_Measures_(film)

    John Crowley and his wife Aileen are a Portland couple with two of their three children suffering from Pompe disease, a genetic anomaly that typically kills most children before their tenth birthdays. John, an advertising executive, contacts Robert Stonehill, a researcher in Nebraska who has done innovative research for an enzyme treatment for ...

  4. Glycogen storage disease type II - Wikipedia

    en.wikipedia.org/wiki/Glycogen_storage_disease...

    The prognosis for individuals with Pompe disease varies according to the onset and severity of symptoms, along with lifestyle factors. Without treatment the infantile form (which can typically be predicted by mutation analysis) of the disease is particularly lethal — in these cases, the time taken to begin treatment is critical, with evidence ...

  5. The 'We Live in Time' director on why the movie made ... - AOL

    www.aol.com/live-time-director-why-movie...

    Andrew Garfield and Florence Pugh star as a couple dealing with a cancer diagnosis in "We Live in Time." BI spoke to director John Crowley about how the film's tone balances romance and melodrama.

  6. William Canfield - Wikipedia

    en.wikipedia.org/wiki/William_Canfield

    William Canfield is a glycobiologist, chief scientific officer and founder of an Oklahoma City-based biotechnology company, Novazyme, which was acquired by Genzyme in August 2001 and developed, among other things, an enzyme that can stabilize (but not cure) Pompe disease, based on Canfield's ongoing research since 1998.

  7. With help from Duke doctors, a rare genetic disease is ... - AOL

    www.aol.com/help-duke-doctors-rare-genetic...

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