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2. Chemotherapy-induced nausea and vomiting - Wikipedia

   en.wikipedia.org/wiki/Chemotherapy-induced...

   A newer class of drugs known as the NK 1 antagonists are a recently developed class of very efficacious drugs for controlling CINV. These drugs are often used alongside 5HT 3 inhibitors and corticosteroids to form a very potent cocktail of antiemetics that verge on achieving a nearly complete patient response (that is, completely stopping CINV ...

3. Cancer and nausea - Wikipedia

   en.wikipedia.org/wiki/Cancer_and_nausea

   A painting from 1681 depicting a person affected by nausea and vomiting. Cancer and nausea are associated in about fifty percent of people affected by cancer. [1] This may be as a result of the cancer itself, or as an effect of the treatment such as chemotherapy, radiation therapy, or other medication such as opiates used for pain relief.

4. NK1 receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/NK1_receptor_antagonist

   Chemotherapy-induced emesis is a major problem in cancer treatment. A new compound, T-2328 (figure 7), a non-peptide antagonist of the tachykinin NK 1 family, is studied for that purpose. T-2328 is administered intravenously, and treats both acute and delayed emesis.

5. Aprepitant - Wikipedia

   en.wikipedia.org/wiki/Aprepitant

   Aprepitant, sold under the brand name Emend among others, is a medication used to prevent chemotherapy-induced nausea and vomiting and to prevent postoperative nausea and vomiting. [5] It may be used together with ondansetron and dexamethasone. [5] It is taken by mouth [5] or administered by intravenous injection. [3]

6. Rolapitant - Wikipedia

   en.wikipedia.org/wiki/Rolapitant

   Rolapitant is used in combination with other antiemetic (anti-vomiting) agents in adults for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including, but not limited to, highly emetogenic chemotherapy. [1] The approved antiemetic combination consists of rolapitant ...

7. List of antineoplastic agents - Wikipedia

   en.wikipedia.org/wiki/List_of_antineoplastic_agents

   Prostate cancer: Myelosuppression, diarrhoea, kidney failure, hypersensitivity, severe GI reactions (including perforation, ileus, colitis, etc.; all rare) and peripheral neuropathy Docetaxel: IV: As above. Breast cancer, non-small cell lung cancer, ovarian cancer, prostate cancer, squamous cell head and neck cancer and gastric cancer.