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Nephrology is the medical specialty which addresses diseases of kidney function: these include CKD, nephritic and nephrotic syndromes, acute kidney injury, and pyelonephritis. Urology addresses diseases of kidney (and urinary tract) anatomy : these include cancer , renal cysts , kidney stones and ureteral stones , and urinary tract obstruction .
Fig.1) Schematic diagram of the nephron (yellow), relevant circulation (red/blue), and the four methods of altering the filtrate. The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts:
Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney. This encompasses all functions of the kidney, including maintenance of acid-base balance; regulation of fluid balance; regulation of sodium, potassium, and other electrolytes; clearance of toxins; absorption of glucose, amino acids, and other small molecules ...
The glomerulus (pl.: glomeruli) is a network of small blood vessels (capillaries) known as a tuft, located at the beginning of a nephron in the kidney. Each of the two kidneys contains about one million nephrons. The tuft is structurally supported by the mesangium (the space between the blood vessels), composed of intraglomerular mesangial cells.
Diagram outlining movement of ions in nephron, with the collecting ducts on the right. The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water. At times of ...
The kidney has many functions, which a well-functioning kidney realizes by filtering blood in a process known as glomerular filtration. A major measure of kidney function is the glomerular filtration rate (GFR). The glomerular filtration rate is the flow rate of filtered fluid through the kidney.
This is an accepted version of this page This is the latest accepted revision, reviewed on 13 November 2024. This article is about the human urinary system. For urinary systems of other vertebrates, see Urinary systems of birds, urinary systems of reptiles, and urinary systems of amphibians. Anatomical system consisting of the kidneys, ureters, urinary bladder, and the urethra Urinary system 1 ...
The kidneys are susceptible to toxic injury, since toxins are reabsorbed in the tubules along with most of the filtered substances. [47] The kidneys are able to restore their functionality after acute injury, but it also can progress into chronic kidney disease. Chronic kidney disease is characterised by loss of function of the kidney tissues ...