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The prostate gets larger in most men as they get older. For a symptom-free man of 46 years, the risk of developing BPH over the next 30 years is 45%. Incidence rates increase from 3 cases per 1000 man-years at age 45–49
The prostate is a exocrine gland of the male reproductive system. In adults, it is about the size of a walnut, [2] and has an average weight of about 11 grams (0.39 oz), usually ranging between 7 and 16 grams (0.25–0.56 oz). [3] The prostate is located in the pelvis. It sits below the urinary bladder and surrounds the urethra.
Prostate cancer is common, with almost 300,000 new diagnoses in the U.S. each year; one in every eight men is diagnosed with it in their lifetime.
In a study of young adults in Greece (aged 21–50, mean age 40.9 years), the prevalence was found to be 7.35%. [4] While among urologic patients in South Korea (aged 29–89, mean age 61.9 years), the prevalence was 40.7%. [5] The prevalence is notably higher in patients with benign prostatic hyperplasia, ranging from 68.8% to 70%. [3]
Gleason 3 is a clearly infiltrative neoplasm, with extension into adjacent healthy prostate tissue. The glands alternate in size and shape, and are often long/angular. They are usually small/micro-glandular in comparison to Gleason 1 or 2 grades. However, some may be medium to large in size.
Prostate cancer is rare in those under 40 years old, [93] and most cases occur in those over 60 years, [2] with the average person diagnosed at 67. [94] The average age of those who die from prostate cancer is 77. [94] Only a minority of prostate cancer cases are diagnosed.
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The most common cause of urinary retention is BPH. This disorder starts around age 50 and symptoms may appear after 10–15 years. BPH is a progressive disorder and narrows the neck of the bladder leading to urinary retention. By the age of 70, almost 10 percent of males have some degree of BPH and 33% have it by the eighth decade of life.