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Multisystem inflammatory syndrome in children (MIS-C), or paediatric inflammatory multisystem syndrome (PIMS / PIMS-TS), or systemic inflammatory syndrome in COVID-19 (SISCoV), is a rare systemic illness involving persistent fever and extreme inflammation following exposure to SARS-CoV-2, the virus responsible for COVID-19. [7]
Children with COVID-19 appear to exhibit similar rates as adults for loss of taste and smell. [45] Kawasaki syndrome , a multi-system inflammatory syndrome, has received extensive attention. [ 1 ] About 16% of children experience some type of neurological manifestation of COVID-19, such as headache or fatigue. [ 45 ]
Significantly more children reported severe anxiety and severe sleep-related impairment during the COVID-19 lockdown than before COVID-19. The results of this study confirm the suspicions of child and youth care professionals that the COVID-19 lockdown has negative effects on the mental and social health of children and adolescents.
Longer-term effects of COVID-19 have become a prevalent aspect of the disease itself. These symptoms can be referred to by many names including post-COVID-19 syndrome, long COVID, and long haulers syndrome. An overall definition of post-COVID conditions (PCC) can be described as a range of symptoms that can last for weeks or months. [83]
This registry based, multi-center, multi-country data provide provisional support for the use of ECMO for COVID-19 associated acute hypoxemic respiratory failure. Given that this is a complex technology that can be resource intense, guidelines exist for the use of ECMO during the COVID-19 pandemic. [85] [86] [87]
The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 , began with an outbreak of COVID-19 in Wuhan, China, in December 2019. Soon after, it spread to other areas of Asia, and then worldwide in early 2020.
SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]
Ambulocetus (Latin ambulare "to walk" + cetus "whale") is a genus of early amphibious cetacean [a] from the Kuldana Formation in Pakistan, roughly 48 or 47 million years ago during the Early Eocene . It contains one species , Ambulocetus natans (Latin natans "swimming"), known solely from a near-complete skeleton.