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[citation needed] Annual cost to the UK National Health Service (NHS) in 2018, for 5–40 mg rosuvastatin daily (of one person) was £24-40, compared to £10-20 for 20–80 mg simvastatin. [38] In 2013, it was the fourth-highest-selling drug in the United States, accounting for approximately $5.2 billion in sales. [39]
The most important adverse side effects are muscle problems, ... Rosuvastatin Simvastatin 10–20% – 20 mg: 10 mg: 10 mg – 5 mg 20–30% – 40 mg:
Serious side effects may include anaphylaxis, liver problems, depression, and muscle breakdown. [4] [5] Use in pregnancy and breastfeeding is of unclear safety. [10] Ezetimibe works by decreasing cholesterol absorption in the intestines. [5] Ezetimibe was approved for medical use in the United States in 2002. [4] It is available as a generic ...
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
Ezetimibe/rosuvastatin, sold under the brand name Ridutrin among others, is a combination medication used to treat high cholesterol. [6] [7] In some countries it is sold as a kit or a pack containing two distinct pills. [8] [9] The combination was approved for medical use in the United States in March 2021. [4]
Side effects [27] Muscle weakness; Fatigue; Rhabdomyolysis; Hepatotoxicity; Used for risk factor control; If the maximum dose of statin cannot achieve the patient's goal, combination with ezetimibe is recommended. [17] An image of rosuvastatin tablets (Crestor) Caution
Common side effects include joint pain, ... which compared the effects of high-dose atorvastatin and rosuvastatin, also ... 20- and 40-mg doses of its generic version ...
Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia.It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US).