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Tamsulosin is taken by mouth. [6] Common side effects include dizziness, headache, insomnia, nausea, blurry vision, and sexual problems. [9] [6] Other side effects may include feeling lightheaded with standing due to changes in blood pressure, and angioedema. [9] Tamsulosin is an alpha blocker and works by relaxing muscles in the prostate. [10]
As discussed above, tamsulosin may have less risk for low blood pressure and orthostatic hypotension due to its selectivity for α 1a-adrenergic receptors. On the other hand, the drug (a) elevates risk for floppy iris syndrome, and (b) might show adverse drug reactions (ADRs) characteristic of the sulfa related drugs.
Alpha 1 blockers cause vasodilation by relaxing smooth muscles that control blood vessel diameter, leading to lower blood pressure. [1] FDA-approved uses of these drugs include treating conditions like benign prostatic hyperplasia, hypertension, pheochromocytoma, extravasation management, and reversal of local anesthesia.
For instance, alpha blockers that are used for the reduction of blood pressure, such as phenoxybenzamine or phentolamine can have synergy with other drugs that affect smooth muscle, blood vessels, or drugs used for erectile dysfunction (i.e. sildenafil, tamsulosin, etc.).
High blood pressure is caused by the force of blood flow in the arteries being too high. The DASH diet includes heart-healthy foods that lower blood pressure.
The authors defined healthy resting blood pressure as a reading below 130 over 85 millimeters of mercury — a measurement of pressure known as mmHg — pre-high blood pressure as ranging from 130 ...